University College of Science, OU

Dr.Vikas Sarma

Dr.Vikas Sarma,

Assistant Professor ( C ),

Department of Biotechnology, University College of Science, Saifabad,

Osmania University , Hyderabad - 500004

Contact Addresses

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Academic Profile

Ph.D in Genetics from Osmania University, Hyderabad, India. Title of the thesis: “Cytogenetic, Biochemical and Molecular Studies in Abnormal Sex Differentiation”.
Qualified State Eligibility Test (TS & AP), conducted by Osmania University.

Current Status

Working as Assistant Professor (C.) in Dept. of Biotechnology at University College of Science, Osmania University, Saifabad, Hyderabad, India.
Teaching M.Sc and B.Sc Biotechnology students in the areas of Human Genetics, Medical Biotechnology, Recombinant DNA technology, Molecular Biology, Microbiology.

Work Experience

Worked as Senior Team Leader –Cytogenetics at Oncquest Laboratories Ltd., New Delhi (A division of Dabur India Ltd.)
Independently handling the cytogenetics department and carried out diagnosis of the genetic disorder by lymphocyte culturing, Bone marrow culturing, GTG banding and FISH diagnosis of the samples received for the cytogenetic analysis. Supervising the lab work, handling Olympus microscope and Cytovision karyotype software for issuing the final karyotype/FISH report were the key responsibilities

Research Experience

Worked on cytogenetic and biochemical analysis part of my PhD work under the supervision of Prof.A.Jyothy, Director, Institute of Genetics and Hospital for Genetic Diseases, Osmania University Hyd.
Worked on molecular analysis part of my PhD work under guidance of Dr.K.Thangaraj, Senior scientist, Centre for Cellular and Molecular Biology, Hyd. Dealing with DNA isolation, PCR, DNA sequencing, genotyping and identification of mutation in abnormalities of human sexual differentiation.
Worked as Research Fellow at Cell Biology Department of Institute of Genetics and Hospital for Genetic Diseases, Osmania University. Involved in the Cytogenetic diagnostic division. Independently handling lymphocyte cultures and chromosomal analysis (karyotyping) by GTG banding and using Leica CW400 software. Dealt with FISH technique for analysis of Down’s, Turner’s and sex chromosomal abnormalities. Simultaneously, involved in teaching Genetics to the nursing college students, and medical college students. Guided M.Sc students for dissertation work.
Worked as Research Assistant at Vasavi Medical and Research centre, Hyd under guidance of Prof.Y.R.Ahuja in Genetics and Molecular Medicine Department and carried out diagnosis by providing karyotyping for patients with chromosomal disorders and also worked on the in-vitro DNA damage studies by the comet assay.

Paper Publications

Vikas Sharma, Y.R.Ahuja, K.Vaidyanath LS-International Journal of Life Sciences Vol 1, Issue 1, Jan-Apr 2012, 1-11.
“Alzheimer Disease”Vikas Sharma, K.Vaidyanath, Y.R.Ahuja Prof.A.P.Akademi of Sciences, Hyderabad Vol.12 (3) 2008; 2“A novel Androgen Receptor Gene mutation in a patient with Congenital Adrenal Hyperplasia associated with Penoscrotal Hypospadias.”Vikas Sharma, Kumarasamy Thangaraj, Akka Jyothy Translational Research Vol 164, issue 2, August 2014, Pages 149-152 (Journal Translational Research with an Impact factor of 5.030)
“A novel insertion-induced frameshift mutation of the androgen receptor gene in a patient with primary amenorrhea” Vikas Sharma, Kumarasamy Thangaraj, Akka Jyothy (Meta Gene Volume 2, December 2014, Pages 11–15)
"A novel Arg615Ser mutation of Androgen Receptor DNA-binding domain in three 46,XY sisters with complete androgen insensitivity syndrome and bilateral inguinal hernia”Vikas Sharma, Rajender Singh, Kumarasamy Thangaraj, Akka Jyothy Fertility and Sterility Vol.95, Issue 2, February 2011, Pages 804.e19-804.e21 (Journal Fertility and Sterility with an Impact Factor of 4.590)
“A Saga of Human Chromosomology: Five decades of Progress in Human Cytogenetics” 46-254.

Project Works / Training Programmes

“Short Term Training Course in Cytogenetics, Plant Molecular Genetics and Plant Tissue Culture”. Hands on training sponsored by Department of Biotechnology from 2nd -13th January, 2012.
Three day student–teacher interactive cum industrial tour based workshop. Sponsored by Department of Biotechnology at PGCS, Osmania University from 10th -12th January, 2011.
“Advanced Training in Genetic Diagnosis and Genetic Counseling” 4th Hands on Training sponsored by Department of Biotechnology at IOG, Osmania University from January 19th-5th February, 2009.
Bio-informatics project on “Genome analysis on HIV virus”. Biology, Genome and gene of HIV. Use of tools like BLAST, COG, Multiple alignment through CLUSTAL W, 3D structure of proteins, Pfam, secondary RNA structure, Validation of results through PUBMED.
“Orientation programme” at “Institute of preventive medicine, Hyd.,”
Training programme at Kamineni hospitals, Hyd.,

Conferences ( Papers/Posters)

Clinical manifestations, diagnosis and management of Androgen Insensitivity Syndrome.Vikas Sharma, K.Thangaraj, A. Jyothy New Frontiers in Diagnosis & Management of Genetic Diseases to be held on January 29th -30th, 2016.
Nanotoxicology: impact on environment and health
D.Alekhya, D.Bhargavi,K.Grace Esther, M.Pooja, M.Srikanth, Vikas Sharma
National Conference on emerging challenges and innovative strategies in fresh water ecology, biodiversity & applied toxicology Sept 26-27, 2014. Nizam College, Hyderabad.
Prenatal Diagnosis: Opportunities and Challenges
P.Sumapriya, D.Jayasree, Vikas Sharma
6th International Conference on Genetic and Molecular Diagnosis in Modern Medicine. February 8-10, 2013. VMRC,Hyderabad.
4.Xenoantiandrogens: A risk factor for androgen receptor mutation in hypospadias.
A.Jyothy, Vikas Sharma, A.Sujatha, Rajender Singh, Kumarasamy Thangaraj
41st Annual Environmental Mutagen Society meeting on "Complex Systems in Biology and Risk Assessment." October 23-27, 2010. Fort Worth, Texas, USA.
5. Primary Amenorrhea and its impact on womens health.
Vikas Sharma, Rajender Singh, Kumarasamy Thangaraj, A.Jyothy
International conference on impact of diseases and social issues affecting women and their amelioration. December 12-14, 2010. IGHGD, Osmania University, Hyderabad.
6. Primary Amenorrhea: Diagnostics and therapeutics- A promising future with nanotechnology.
Vikas Sharma, A.Jyothy, K.Vaidyanath
International conference on recent trends in nano and bio-sciences. February 24-26,2010. PGCS, Osmania University, Hyderabad.
7. Cytogenetic evaluation of Primary Amennorhea
Vikas Sharma,A. Venkateshwari, M.Sujatha, M.Srinivas Rao, A.Jyothy;
I AP Science Congress November 14th-16th 2008, Osmania University, Hyderabad.
8. Relation of serum C-reactive protein, TNF-α concentrations and effect of the G-308A TNF-α polymorphisms in MI patients and their first degree relatives.
B.M.V.Srikanth Babu, J.Yashovanthi , H.Surekha Rani, B.PullaReddy, Vikas Sharma, , G.Madhavi, Venkata Karunakar, A. Venkateshwari, V. Daya Sagar Rao, A.Jyothy;
XXXIII Annual Conference of ISHG and International Symposium on Genetics Revisited: the Genomics and proteomics advantage February 11th-13th 2008, Andhra University, Vishakapatnam.
Oxidative stress and total anti oxidant status in myocardial infarction patients and first degree relatives.
B.M.V.Srikanth Babu, H.Surekha Rani, B.PullaReddy, Vikas Sharma, J.Yashovanthi, G.Madhavi, A.Venkateshwari, K.Venkata Karunakar, Daya Sagar Rao, A.Jyothy; National seminar on “genome Analysis perspective in the post genomic era and its relevance to society October 26th-28th 2007, MGNIRSA Hyderabad.
10. Cytogenetic evaluation of Patients with abnormalities of sexual differentiation. Vikas Sharma, M.Swarna, B.Umadevi, H.Surekha Rani, M.Sujatha & A.Jyothy Symposium on Chromosome to Genome July 3rd – 5th 2007,CCMB, Hyderabad
Chromosomal analysis in couples with bad obstetric history.
Vikas Sharma, H.Surekha Rani & A.Jyothy ;National Conference on Genomic Impact on Human Health February 2nd-3rd 2007,Osmania university, Hyderabad.12. Role of Interleukin 10, 1082G polymorphisms in coronary artery disease B.M.V.Srikanth Babu, , H.Surekha Rani, Vikas Sharma, B.PullaReddy, G.Madhavi, J.Yashovanthi,K.Venkata Karunakar, Daya Sagar Rao, A.Jyothy;National Conference on Genomic Impact on Human Health February 2nd-3rd 2007, Osmania university, Hyderabad.
Congenital Adrenal Hyperplasia-A case study
Vikas Sharma, H.Surekha Rani, M.Sujatha & A.Jyothy ; XII All India Conference in Cytology and Genetics December 8th-10th 2005, Andhra University, Vishakapatnam.
Oxidant and antioxidant status in Diabetes
G.madhavi, H.Surekha Rani, Vikas Sharma, A Jyothy; International conference on Human Genome Update August 28th –30th , IOG, Hyderabad.

Seminars Attended

1. Emerging trends, challenges and innovative approaches in clinical research in India, BMMRC 27th – 28th April 2013, Hyderabad.
2. Advances in prenatal diagnosis of birth defects and new born screening, IOG, Osmania University, August 20th, 2011, Hyderabad.
3. Environment, Health and Biodiversity, IOG, Osmania University, June 5th, 2007, Hyderabad.
4. Recent Trends in Genetic Diagnosis and Counseling, IOG, Osmania University, January 31st, 2006, Hyderabad.
5. Critical issues in the diagnosis and management of childhood genetic diseases:special reference to Thalassaemias and Muscular Dystrophy, IOG, Osmania University, February 28th, 2005, Hyderabad.
6. Seminar on Biotechnology and its application, Bhavan’s New Science College February 5th, 2005, Hyderabad.

University College of Science, Saifabad, Osmania University,Hyderabad-500004,INDIA
Phone: + 91-040-23393530; 23375395; 23306136, Email: oupgcss@gmail.com